{"id":4922,"date":"2023-09-14T10:52:37","date_gmt":"2023-09-14T03:52:37","guid":{"rendered":"http:\/\/localhost\/chem\/?p=4922"},"modified":"2026-03-02T14:34:38","modified_gmt":"2026-03-02T07:34:38","slug":"asst-prof-dr-panupun-limpachayaporn","status":"publish","type":"post","link":"https:\/\/chem.sc.su.ac.th\/?p=4922&lang=en","title":{"rendered":"Asst. Prof. Dr. Panupun Limpachayaporn"},"content":{"rendered":"
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Email:<\/span> limpachayaporn_p@su.ac.th<\/h4>\n

Room:<\/span> 1145 Science Building 1<\/h4>\n

Tel.:<\/span> 034-147008<\/h4>\n

Fax:<\/span> 034-147002<\/h4>\n

Website:
\n<\/span>https:\/\/scholar.google.com\/citations?user=sJ4sVuEAAAAJ&hl=en<\/a><\/h4>\n

Education:<\/span><\/strong><\/h3>\n

Dr. rer. nat. (Chemistry) University of M\u00fcnster, Germany <\/h4>\n

Diplom (Chemie) University of G\u00f6ttingen, Germany <\/h4>\n

B.Sc. (Chemistry) Silpakorn University, Thailand <\/h4>\n<\/div>\n<\/div><\/div><\/div><\/div>
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Research Interest:<\/span><\/strong>:<\/h3>\n
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  • Synthesis and Cytotoxicity towards Various Cancer Cell Lines of Sorafenib Analogues<\/li>\n
  • Development of Heterocylic Fragments as Anti-Cancer and Anti-Microbial Agents<\/li>\n
  • Structural Modifications of Bioactive Natural Products for Improvement of Biological Activities<\/li>\n<\/ul>\n

    Publications:<\/span><\/strong>:<\/h3>\n
      \n
    • \n

      Singpanna, K., Limpachayaporn, P.<\/strong><\/span>, Sukma, M., Athipornchai, A., Nuntharatanapong, N. (2022). \u201cSynthesis of Fluorinated N- Benzylaniline Derivatives and Evaluations on Anti-Tyrosinase and Anti-Melanogenic Activities.\u201d Key Engineering Materials,<\/strong><\/span> 914: 87-92.<\/h4>\n<\/li>\n
    • \n

      Oekchuae, S., Sirirak, J., Charoensuksai, P., Wongprayoon, P., Chuaypen, N., Boonsombat, J., Ruchirawat, S., Tangkijvanich, P., Suksamrarn, A., Limpachayaporn, P.<\/strong><\/span> (2022). \u201cThe Design and Synthesis of a New Series of 1,2,3-Triazole-Cored Structures Tethering Aryl Urea and Their Highly Selective Cytotoxicity toward HepG2.\u201d Pharmaceuticals,<\/strong><\/span> 15: 504. (Scopus)<\/h4>\n<\/li>\n
    • \n

      Wongprayoon, P., Leelasart, S., Jantham, J., Pootaeng-on, Y., Oekchuae, S., Limpachayaporn, P.<\/span>,<\/strong> Rayanil, K., Charoensuksai, P. (2022). \u201cA triterpenoid friedelan-3\u00df-ol isolated from Euphorbia lactea exhibited cytotoxic activity against HN22 cells by inducing an S-phase cell cycle arrest.\u201d Journal of Applied Pharmaceutical Science,<\/strong><\/span> 12(10): 031-048.<\/h4>\n<\/li>\n
    • \n

      Pengnam, S., Wongprayoon, P., Limpachayaporn, P.<\/span>,<\/strong> Rayanil, K., Charoensuksai, P. (2022). \u201cSynergistic activity of friedelan-3\u03b2-ol isolated from Euphorbia lactea and doxorubicin against MDA-MB-231 breast cancer cell line.\u201d Science, Engineering and Health Studies,<\/strong><\/span> 16: 22050011.<\/h4>\n<\/li>\n
    • \n

      Limpachayaporn, P.<\/span>,<\/strong> Nuchpun, S., Sirirak, J., Charoensuksai, P., Wongprayoon, P., Chuaypen, N., Tangkijvanich, P., Suksamrarn, A. (2022) \u201cmeta-Ureidophenoxy-1,2,3-triazole hybrid as a novel scaffold for promising HepG2 hepatocellular carcinoma inhibitors: Synthesis, biological evaluation and molecular docking studies.\u201d Bioorganic & Medicinal Chemistry,<\/strong><\/span> 74, 117048. (ISI)<\/h4>\n<\/li>\n
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      Singpanna, K., Dechsri, K., Patrojanasophon, P., Limpachayaporn, P.<\/span>,<\/strong> Opanasopit, P., Nuntharatanapong, N. (2021). \u201cTransdermal delivery, cytotoxicity and anti-melanogenic activity of p-chlorophenyl benzyl ether loaded-liposomes.\u201d Journal of Drug Delivery Science and Technology,<\/strong><\/span> 65: 102746. (Scopus)<\/h4>\n<\/li>\n
    • \n

      Palakhachane, S., Ketkaew, Y., Chuaypen, N., Sirirak, J., Boonsombat, J., Ruchirawat, S., Tangkijvanich, P., Suksamrarn, A., Limpachayaporn, P.<\/strong><\/span> (2021). \u201cSynthesis of sorafenib analogues incorporating a 1, 2, 3-triazole ring and cytotoxicity towards hepatocellular carcinoma cell lines.\u201d Bioorganic Chemistry,<\/strong><\/span> 112: 104831. (Scopus)<\/h4>\n<\/li>\n
    • \n

      Matako, Y., Suttisingtong, K., Boonsombat, J., Sirirak, J., Limpachayaporn, P.<\/strong><\/span> (2021). \u201cThe Synthetic Pathways of a New 1,2,3-Triazole-Containing Sorafenib Analogue and Its Cytotoxicity towards Cancer Cell Lines.\u201d Rajamangala University of Technology Srivijaya Research Journal,<\/strong><\/span> 13(1): 244-258. (TCI 1)<\/h4>\n<\/li>\n
    • \n

      Singpanna, K., Nuntharatanapong, N., Rojanarata, T., Limpachayaporn, P.<\/span>,<\/strong> Patrojanasophon, P., Opanasopit, P. (2021). \u201cDevelopment and evaluation of p-chlorophenyl benzyl ether-loaded microemulsions for transdermal delivery.\u201d Journal of Current Science and Technology<\/strong>,<\/span> 11(1): 90-99. (Scopus)<\/h4>\n<\/li>\n
    • \n

      Singpanna, K., Oekchuae, S., Jareonkunmetee, K., Athipornchai, A., Nuntharatanapong, N., Opanasopit, P., Limpachayaporn, P. <\/strong><\/span>(2020). \u201cSYNTHESIS AND ANTI-TYROSINASE ACTIVITY EVALUATION OF FLUORINATED CHALCONE AND PHENYL BENZYL ETHER DERIVATIVES.\u201d Thai Bull Pharm Sci,<\/strong><\/span> 15(1): 81-89.<\/h4>\n<\/li>\n
    • \n

      Riam- Amatakun, W. , Limpachayaporn, P.<\/span>, <\/strong>Pizon, J. R. L. , Opanasopit, P., Nuntharatanapon, N. (August 2019). \u201cAnti-melanogenic activity of p-chlorophenyl benzyl ether in \u03b1-msh-induced mouse melanoma b16f10 cells.\u201d Proceedings of International Conference and Exhibition on Pharmaceutical Sciences and Technology (PST 2019), Key Engineering Materials,<\/strong><\/span> 819, 118-123. June 18-19, 2019. Bangkok, Thailand.<\/h4>\n<\/li>\n
    • \n

      Palakhachane, S., Ketkaew, Y., Chuaypen, N., Tangkijvanich, P., Suksamrarn, A., Limpachayaporn, P.<\/strong><\/span> (2019). \u201cThe preliminary studies on the synthesis and the cytotoxicity towards HepG2 and Huh7 of a new series of sorafenib analogues: Replacement of aryl urea with a triazole ring.\u201d in Proceedings of the 45th Congress on Science and Technology of Thailand (STT45), 348-358. October 7-9, 2019. Mae Fah Luang University, Chiang Rai, Thailand.<\/h4>\n<\/li>\n
    • \n

      Suppharatthanya, P., Chaneam, S., Limpachayaporn, P.,<\/strong><\/span> Jitnapa S. (2019). \u201cKinetics and Isotherm Study of the Adsorption of Brazilien from Sappanwood on Montmorillonite.\u201d \u0e27\u0e32\u0e23\u0e2a\u0e32\u0e23\u0e27\u0e34\u0e17\u0e22\u0e32\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e41\u0e25\u0e30\u0e40\u0e17\u0e04\u0e42\u0e19\u0e42\u0e25\u0e22\u0e35,<\/strong><\/span> (27): 989-1001. (TCI-1)<\/h4>\n<\/li>\n
    • \n

      Riam-Amatakun, W., Limpachayaporn, P.<\/span>,<\/strong> Rhea L. Pizon, J., Opanasopit, P., Nuntharatanapong, N. (2019). \u201cAnti-Melanogenic Activity of p-Chlorophenyl Benzyl Ether in\u03b1-MSH-Induced Mouse Melanoma B16F10 Cells.\u201d Key Engineering Materials,<\/strong><\/span> 2019 (819): 118-123. (Conference paper, Scopus)<\/h4>\n<\/li>\n
    • \n

      Suttisintong, K., Palakhachane, S., Athipornchai, A., Pimtomg, W., Limpachayaporn, P.<\/strong><\/span> (2018). \u201cSynthesis and evaluation of anti-tyrosinase activity of phenyl benzyl ether derivatives: Effects of functional groups and their positions.\u201d Science, Engineering and Health Studies,<\/strong><\/span> 12(2): 111-123.<\/h4>\n<\/li>\n
    • \n

      Klinpetch, W., Petdum, A., Thavornpradit, S., Panchan, W., Sooksimuang, T., Sirirak, J., Suvokhiaw, S., Limpachayaporn, P<\/strong>.<\/span>, Wanichacheva, N. (2018). \u201cFluorometric and colorimetric Hg2+ -sensor via FRET system of pentahelicene donor and rhodamine B acceptors.\u201d Proceedings of the 2018 Chemistry Research Symposium (ChRS2018), 5-10. May 26-27, 2018. Chemistry Division, Faculty of Liberal Arts and Science, Kasetsart University Kamphaeng Saen Campus, Nakhon Pathom, Thailand.<\/h4>\n<\/li>\n
    • \n

      Limpachayaporn, P.<\/span>,<\/strong> Sch\u00e4fers, M., Haufe, G. (2015). \u201cIsatin sulfonamides: Potent caspases-3 and -7 inhibitors and promising PET and SPECT radiotracers for apoptosis imaging.\u201d Future Medicinal Chemistry,<\/strong> <\/span>7(9): 1173-1196.<\/h4>\n<\/li>\n
    • \n

      Limpachayaporn, P.<\/span>,<\/strong> Wagner, S., Kopka, K., Schober, O., Sch\u00e4fers, M., Haufe, G. (2014). \u201cSynthesis of 7-halogenated isatin sulfonamides: Nonradioactive counterparts of caspase-3\/-7 inhibitor-based potential radiopharmaceuticals for molecular imaging of apoptosis.\u201d Journal of Medicinal Chemistry,<\/strong><\/span> 57(22): 9383-9395.<\/h4>\n<\/li>\n
    • \n

      Limpachayaporn, P.<\/span>,<\/strong> Sch\u00e4fers, M., Schober, O., Kopka, K., Haufe, G. (2013). \u201cSynthesis of new fluorinated, 2-substituted 5-pyrrolidinylsulfonyl isatin derivatives as caspase-3 and caspase-7 inhibitors: Nonradioactive counterparts of putative PET-compatible apoptosis imaging agents.\u201d Bioorganic and Medicinal Chemistry,<\/strong><\/span> 21(7): 2025-2036.<\/h4>\n<\/li>\n
    • \n

      Limpachayaporn, P.<\/span>,<\/strong> Riemann, B., Kopka, K., Schober, O., Sch\u00e4fers, M., Haufe, G. (2013). \u201cInfluence of 4- or 5-substituents on the pyrrolidine ring of 5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin derivatives on their inhibitory activities towards caspases-3 and -7.\u201d European Journal of Medicinal Chemistry,<\/strong><\/span> 64: 562-578.<\/h4>\n<\/li>\n
    • \n

      Limpachayaporn, P<\/strong>.<\/span>, Wagner, S., Kopka, K., Hermann, S., Sch\u00e4fers, M., Haufe, G. (2013). \u201cSynthesis, 18F-radiolabeling, and in vivo biodistribution studies of N-fluorohydroxybutyl isatin sulfonamides using positron emission tomography.\u201d Journal of Medicinal Chemistry<\/strong>,<\/span> 56(11): 4509-4520.<\/h4>\n<\/li>\n<\/ul>\n<\/div>\n<\/div><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"

      Email: limpachayaporn_p@su.ac.th Room: 1145 Science Building 1 Tel.: 034-147008 Fax: 034-147002 Website: https:\/\/scholar.google.com\/citations?user=sJ4sVuEAAAAJ&hl=en Education: Dr. rer. nat. (Chemistry) University of M\u00fcnster, Germany Diplom (Chemie) University of G\u00f6ttingen, Germany B.Sc. (Chemistry) Silpakorn University, Thailand Research Interest:: Synthesis and Cytotoxicity towards Various Cancer Cell Lines of Sorafenib Analogues Development of Heterocylic Fragments as Anti-Cancer and Anti-Microbial Agents […]<\/p>\n","protected":false},"author":11,"featured_media":6851,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[110],"tags":[],"class_list":["post-4922","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-organic-chemistry"],"_links":{"self":[{"href":"https:\/\/chem.sc.su.ac.th\/index.php?rest_route=\/wp\/v2\/posts\/4922","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/chem.sc.su.ac.th\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/chem.sc.su.ac.th\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/chem.sc.su.ac.th\/index.php?rest_route=\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/chem.sc.su.ac.th\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=4922"}],"version-history":[{"count":3,"href":"https:\/\/chem.sc.su.ac.th\/index.php?rest_route=\/wp\/v2\/posts\/4922\/revisions"}],"predecessor-version":[{"id":6888,"href":"https:\/\/chem.sc.su.ac.th\/index.php?rest_route=\/wp\/v2\/posts\/4922\/revisions\/6888"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/chem.sc.su.ac.th\/index.php?rest_route=\/wp\/v2\/media\/6851"}],"wp:attachment":[{"href":"https:\/\/chem.sc.su.ac.th\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=4922"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/chem.sc.su.ac.th\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=4922"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/chem.sc.su.ac.th\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=4922"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}